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Famzoa Group

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Decentralized Pharmacy and the 3D-Printed "Polypill"

The pharmaceutical industry in 2026 is moving toward Point-of-Care (PoC) manufacturing, where medications are printed directly in hospital pharmacies to meet the specific pharmacokinetic needs of the patient.

  • The Polypill Concept: For geriatric or complex-care patients taking 10+ daily medications, 3D printing allows for the consolidation of these drugs into a single tablet. Using Semi-Solid Extrusion (SSE) or Fused Deposition Modeling (FDM), different active pharmaceutical ingredients (APIs) are layered within the pill. Each layer can have a distinct "dissolution profile"—for example, one drug may be engineered for rapid release in the stomach, while another is coated for delayed release in the small intestine.

  • Precision Dosing for Pediatric and Renal Care: Traditional mass-produced tablets often lack the low-dose increments required for children or patients with reduced kidney function. 3D printing allows pharmacists to print precise, non-standard dosages (e.g., a 6.25mg dose of a medication usually only available in 10mg increments), reducing the risk of toxicity and side effects.

  • Regulatory and Quality Control: In 2026, the FDA's Framework for 3D Printed Drugs mandates rigorous in-process testing. Hospital-based printers are equipped with real-time vision systems that check the dimensions, weight, and drug-loading consistency of every pill, ensuring they meet the same USP (United States Pharmacopeia) standards as industrial factories.

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